Boosting was a time dependent covariate whose value changed from “non-boosted” to “boosted” 14 days after receipt of a vaccine booster,
Since many cases occur during the "two week worry window", the immune system issues caused by the booster in the first two weeks would cause an overcount in the "2 shot" cohort and an undercount in the "boosted" cohort.
Since omicron has enough mutations to evade natural immunity, everyone is going to get it. Those with original natural immunity seem to bounce back a lot faster based on my limited dataset.
Some context, this is healthcare workers in Cleveland. No distinction is made between those who got infected prior to vaccinated vs. after vaccination.
My guess is cohort-shifting.
Boosting was a time dependent covariate whose value changed from “non-boosted” to “boosted” 14 days after receipt of a vaccine booster,
Since many cases occur during the "two week worry window", the immune system issues caused by the booster in the first two weeks would cause an overcount in the "2 shot" cohort and an undercount in the "boosted" cohort.
Since omicron has enough mutations to evade natural immunity, everyone is going to get it. Those with original natural immunity seem to bounce back a lot faster based on my limited dataset.
Some context, this is healthcare workers in Cleveland. No distinction is made between those who got infected prior to vaccinated vs. after vaccination.