The United States Food and Drug Administration has officially approved Merck’s Molnupiravir for Emergency Use Authorization. Oh boy, this should be a controversial one. On November 30th, an FDA panel of advisors narrowly approved the recommendation for EUA in a
The second-half negative efficacy during the trial was impressive, but seems to be more a factor of the placebo group suddenly performing better while Molnupiravir severe outcome rate was steady. Doesn't seem to matter. The drug probably doesn't make a huge difference to infection outcomes, it's just a scapegoat for the cancers that the Covid-vaccinated were already going to get anyway.
The Organic Consumers Association and National Vaccine Information organisation today got excluded from Paypal. They can no longer get donation through Paypal. That desparate is the government to get the poison in all that they try to cut off everyone who does not comply.
Thanks, great analysis. One of the things I worry about not knowing is why a specific cohort in the Pfizer trial was 18% smaller in size from the placebo when that cohort had a -20.5 vaccine efficacy. It's very suspicious that randomization lead this kind of distribution. Perhaps it's expected given 22 thousand had to be randomized and very few people were baseline Sars-cov-2 positive but this group had the highest incidence density and lowest efficacy. Not represented well in the trials, while we live in a world where the efficacy in this group matters because most of the world is in this group now. Just like you showed how at risk groups can be gamed by randomizing morbidity, I'm of the opinion that something was wrong with the trial randomization for Pfizer where this crucial group was kind of small for Pfizer or people differentially dropped out.
This approval is as shocking as "Covid Vax" approval. A potentially very dangerous, novel treatment that barely works, was approved despite a split decision. Patients followed up only for 29 days.
FDA needs to be disbanded.
Thanks for doing hard work and writing an excellent article.
The second-half negative efficacy during the trial was impressive, but seems to be more a factor of the placebo group suddenly performing better while Molnupiravir severe outcome rate was steady. Doesn't seem to matter. The drug probably doesn't make a huge difference to infection outcomes, it's just a scapegoat for the cancers that the Covid-vaccinated were already going to get anyway.
The Organic Consumers Association and National Vaccine Information organisation today got excluded from Paypal. They can no longer get donation through Paypal. That desparate is the government to get the poison in all that they try to cut off everyone who does not comply.
Aren’t these also required to be taken with another drug or three?
I like how you boil it down: garbage. I have no doubt. Thanks for your work.
Thanks, great analysis. One of the things I worry about not knowing is why a specific cohort in the Pfizer trial was 18% smaller in size from the placebo when that cohort had a -20.5 vaccine efficacy. It's very suspicious that randomization lead this kind of distribution. Perhaps it's expected given 22 thousand had to be randomized and very few people were baseline Sars-cov-2 positive but this group had the highest incidence density and lowest efficacy. Not represented well in the trials, while we live in a world where the efficacy in this group matters because most of the world is in this group now. Just like you showed how at risk groups can be gamed by randomizing morbidity, I'm of the opinion that something was wrong with the trial randomization for Pfizer where this crucial group was kind of small for Pfizer or people differentially dropped out.
Thank you for this article!
I read a tweet by James Hildreth who voted no.
This approval is as shocking as "Covid Vax" approval. A potentially very dangerous, novel treatment that barely works, was approved despite a split decision. Patients followed up only for 29 days.
FDA needs to be disbanded.
Thanks for doing hard work and writing an excellent article.
If I tried to advance this "cure" they would put me away.